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Daily briefing: Who needs testosterone therapy?

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Torn pages from academic books scattered amongst the rubble from the explosion at Sharif University of Technology.

Sharif University of Technology after it was bombed on 7 April 2026.Credit: Fatemeh Bahrami/Anadolu via Getty

Bombing by the United States and Israel have damaged some of Iran’s universities and hospitals, researchers tell Nature. One of the damaged institutions is the Shefa Neuroscience Research Center in Tehran, according to Ali Gorji, a neuroscientist in Germany who supervises PhD students at the Shefa centre. “If attacks on universities become a normal thing, then they can happen in any future stupid war. And this idea is much more destructive than attacking a single building,” he says. A White House spokesperson and a representative of Israel’s military separately told Nature that they do not target civilian infrastructure, but did not explain why these and other institutions were bombed.

Nature | 8 min read

All life on Earth depends on the same molecular alphabet: 20 amino acids that cells string together to make proteins. But now, scientists have engineered bacteria to run a core part of their cellular machinery — the ribosome — with just 19 of those amino acids. Researchers took advantage of recent advances in generative artificial intelligence to create proteins that worked without the amino acid isoleucine. The work offers a blueprint for engineering cells with capabilities beyond those found in nature, the team says, while also hinting at a simpler past when early life relied on a more limited set of building blocks.

Nature | 6 min read

Reference: Science paper

US lawmakers have voted to cut science spending in 2027 from 2026 levels but declined to approve cuts as large as those sought by the administration of US President Donald Trump. Members of the House of Representatives voted to cut the National Science Foundation’s spending in 2027 by 20%, rather than the 55% proposed by the Trump team, for example. The Senate will draft its own version of spending legislation in the next few months, and then the House and Senate will hammer out any differences between their proposals. Regardless of what they decide, some scientists worry that the White House Office of Management and Budget could still delay the release of money to science agencies, as it did in 2026.

Nature | 7 min read

Fifteen years after Japan’s worst nuclear-power accident, construction is under way for the Fukushima Institute for Research, Education and Innovation (F-REI) in Namie, a small town that was evacuated because of concerns about radiation exposure. The institute will focus on robotics, agriculture, the medical uses of radiation and environmental recovery from nuclear disasters.

Nature | 6 min read

Image of the week

A 3D fluorescence image of a single rumen ciliate, Entodinium caudatum.

The newly discovered organelle was found in ciliates (such Entodinium caudatum, pictured). These eukaryotic organisms live in the rumen of herbivores.Credit: Chuanqi Jiang, Jinying He & Che Hu/Inst. of Hydrobiology, CAS

Scientists have identified a previously unknown type of cellular organelle inside microbes that live in the guts of ruminant animals such as sheep and cows. The newly discovered organelle was found in rumen ciliates (such as Entodinium caudatum, pictured). It removes oxygen and releases hydrogen, which archaea in the rumen use as fuel to produce methane. Burping livestock contribute around 30% of global methane emissions produced by human activities, and the authors say their discovery could inspire new ways to reduce these emissions. (Nature | 6 min read)Reference: Science paper (Chuanqi Jiang, Jinying He & Che Hu/Inst. of Hydrobiology, CAS)

European Research Council

News

The European Research Council (ERC) has reversed a policy it introduced to help to deal with a deluge of applications to its coveted awards, after a huge researcher backlash against the measure. The ERC’s plan might have meant some unsuccessful applicants having to wait up to 4 years before they could apply for funding again. Critics argued that longer exclusion periods risked discouraging bold ideas and pushing talent away from Europe. But the ERC — along with many other funders — still has to grapple with the influx of applications, which some blame on the grant-writing prowess of generative AI.

Nature | 6 min read

Opinion

The ERC’s proposals suggest that the system lacks the capacity to handle the growing ambition of European science, says João Conde, a biomedical researcher at NOVA University Lisbon. “Instead of expanding its capacity, the ERC is raising barriers that will keep people out,” he argues.

Nature | 7 min read

Features & opinion

Roxani on the boat handling a fishing net tangled on a ray's tail with a pile of nets in the background.

A marbled ray (Dasyatis marmorata) is found in a catch.Credit: Ugo Mellone for Nature

Many of the fishers in the Amvrakikos Gulf in Greece participate in the conservation project By ElasmoCatch. They allow researchers such as marine scientist Roxani Naasan Aga-Spyridopoulou on board their boats to collect data on shark and ray species they occasionally catch. Her work has shown that, when handled with care, these creatures can survive a trip through a fisher’s net. “The results show that when handling is done correctly, the short-term survival rate is very high — for some species, over 95%,” she says.

Nature | Leisurely scroll

As the United States considers loosening its rules around which men can access testosterone therapy, the hormone is increasingly being promoted by people promising fitter bodies and a boost in energy levels. But there are risks: at high doses, testosterone can be addictive and cause heart problems, infertility and even psychosis. For women, the hormone seems to help with low sexual desire after menopause that causes distress. But the wider benefits are unclear, and muddied by the “incredible placebo effect” of just being listened to by a physician, says endocrinologist Susan Davis. Ultimately, more research is needed to see what widespread use of testosterone might achieve. “If you treat all men with low testosterone, will it actually prevent ill health? We haven’t proved that,” says endocrinologist Bu Yeap.

Nature | 16 min read

Half of all food consumed depends on synthetic nitrogen fertilizers, which rely on natural gas — supplies of which are being roiled by war and global crises. To safeguard the global food system, a group of researchers argues that support should be provided to enable countries should be supported to hold strategic fertilizer reserves, farmers to apply products with care, and industry to roll out fossil-fuel-free alternatives.

Nature | 14 min read

Quote of the day

Don’t just teach scientific progress from the perspective of the ‘winners’, argues philosopher of science Vanessa Seifert — we need to learn about the history of science to understand how our best theories came about. (Chemistry World | 8 min read)

In Friday’s penguin search, Leif Penguinson was hiding somewhere in Gobi Gurvansaikhan National Park in Mongolia. Did you find the penguin? When you’re ready, here’s the answer.

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