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HomeNatureThe heart’s pumping motion seems to keep cancer at bay

The heart’s pumping motion seems to keep cancer at bay

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Illustration of a Nanaimoteuthis sp. extinct cephalopod, swimming in dimly lit waters of a prehistoric sea, showing feeding tentacles extended.

Artist’s impression of an extinct Nanaimoteuthis species, often called krakens, which could have rivalled large marine reptiles in terms of size.Credit: Masato Hattori/Science Photo Library

In the age of dinosaurs, giant octopuses — sometimes named krakens after the mythological monsters — might have grown to nearly 19 metres in length. The estimate is based on fossilized jaws, which researchers say show patterns of wear that came from devouring animals that had hard shells and skeletons. The team suggest that these giant cephalopods might have sat at the top of the marine food chain in the Cretaceous period alongside huge marine reptiles such as mosasaurs. But other researchers say that estimates about the size of the soft-bodied creatures, and how they hunted, should be taken with a pinch of salt.

Nature | 4 min read

Reference: Science paper

In mice, the mechanical action of the heart beating stops tumours from growing — which could explain why heart cancers are so rare in all mammals. Researchers compared a non-beating heart that had been transplanted onto the necks of mice with the ‘native’ hearts in the animals. After being injected with cancer cells, the external hearts were swiftly taken over by the disease, while the beating hearts stayed much closer to cancer-free. But there is a downside: pumping also seems to stop the heart from regenerating like other tissue can.

Nature | 4 min read

Reference: Science paper

18.3 million

The number of children who have been vaccinated since 2023 by the Big Catch-Up programme, a global drive to reverse pandemic-related declines in childhood immunization. (STAT | 1 min read)

The National Science Library of the Chinese Academy of Sciences (CAS) has quietly stopped publishing its influential journal ranking, taking many researchers by surprise. The ranking has had a central role in research evaluation in the country for more than 20 years. Last month, some of the team who used to run the CAS system published a new privately-run index, called Xinrui Scholar, using the CAS ranking methodology. But no one’s sure if it will catch on, and some scholars would seize the moment to move research evaluation beyond journal metrics.

Nature | 7 min read

Two thousand graduate student workers went on strike at Harvard University this week, calling for higher wages, protections for international students at risk of deportation and other changes. The aim of the strike is to halt scientific research at the university, says Laila Norford, a PhD candidate who studies biomedical informatics. “We’re doing essential work that is bringing funding into this university,” she says, “and we’re not seeing the respect returned to us.” A separate union, which represents postdocs, lecturers, teaching assistants and more, could soon join the strike.

Nature | 6 min read

Features & opinion

As scientists reel from the news that data from the influential UK Biobank system was found listed for sale on the Chinese e-commerce site Alibaba, Nature Medicine investigates how the geopolitics driving artificial intelligence superpowers is reshaping biomedical data sets, and who has access to them. Ultimately, says computational medicine researcher Alex Frangi, a balance must be struck between protecting national data and ensuring global inclusivity to ensure data are “a tool for universal clinical progress rather than a source of new health inequalities”.

BBC | 7 min read & Nature Medicine | 16 min read

An alien enthusiast learns that expectation is better than reality in Waiting for them and feeling becomes an act of rebellion in The memory dealer of Old Jeddah.

Nature | 6 min read & Nature | 5 min read

Andrew Robinson’s pick of the top five science books to read this week includes a scientist’s guide to the magic above our heads and an analysis of the five essential ingredients that make a great scientific team.

Nature | 4 min read

‘Ace’, a robotic arm, leverages the power of artificial intelligence to take on elite table-tennis players. A high-speed perception system allows it to predict complex ball movements, all while making sure it doesn’t hit the table, or any surrounding people. But don’t worry table-tennis players, Ace isn’t coming for your job. “This is very much a research project and it was built on the hypothesis that it would challenge us to push the individual component technologies to their limits,” says Peter Dürr, lead engineer on the Ace project.

Nature Podcast | 26 min listen

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Quote of the day

Paul McCarthy, who runs an academic data and recruitment firm in Australia, notes that the number of PhD graduates increasingly outnumbers the available academic posts — possibly contributing to a generational divide in attitudes to the research landscape revealed by a Nature Index survey of researchers. (22 min read)

Today Leif Penguinson is hiding amongst the forests, lakes and abundant outcrops of serpentinite rock in the Parco Naturale Mont Avic in Italy. Can you find the penguin?

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