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This brain structure filters which thoughts we become aware of

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Colourful 3D MRI scan of a healthy human brain.

The inner structures of the brain are difficult to investigate without surgery.Credit: K H Fung/Science Photo Library

Neuroscientists have observed for the first time how structures deep in the brain are activated when the brain becomes aware of its own thoughts. People who had thin electrodes injected deep into their brains as part of a treatment for headaches allowed scientists to study their brain signals and measure conscious awareness. The study found that a deep-brain structure called the thalamus filters which thoughts we become aware of and which we don’t.

Nature | 4 min read

Reference: Science paper

The journal Bioengineered, which was inundated with paper-mill submissions in 2021 — and claimed in 2023 that it had tackled the problem — still harbours hundreds of dubious papers. An analysis by research-integrity sleuths found at least 226 studies on rodents contain copy-and-pasted images and other hallmarks of paper mills. Publisher Taylor & Francis says that it is investigating.

Nature | 6 min read

Reference: arXiv preprint (not peer reviewed)

Trump’s impact on US science

Using words such as “regret” and “mutilation”, the administration of US president Donald Trump has directed the US National Institutes of Health (NIH) to “fund research on a few specific areas” of transgender health that target possible negative consequences of gender-affirming care and surgery. The directive’s specificity, inflammatory language and focus on a hyper-polarizing topic are unprecedented, say NIH employees. The administration has ended NIH funding to nearly every other research project on transgender health. If these proposed studies move forwards, it will create a “a distorted research ecosystem where only politically favourable findings are permitted to exist” and an “evidence vacuum for clinicians who are trying to do right by their patients”, says Harry Barbee, who studies the health of people from gender and sexual minorities.

Nature | 6 min read

The Trump administration’s sweeping tariffs on imports into the United States — which range from 10% on products from some countries up to 54% on goods from China — are increasing the costs of labware and specialist scientific instruments in the country. The tariffs are landing at a time when research institutions are already stretched by Trump’s other cuts. “These aren’t luxury items,” says Tinglong Dai, who researches global supply chains and healthcare. “They’re the core infrastructure of modern science.”

Nature | 5 min read

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Notable quotable

Around 1,900 members of the National Academies of Sciences, Engineering, and Medicine — making up a who’s who of US science — have published an open letter addressed to the American people arguing that the US research enterprise is being destabilized by Trump administration and that a “a climate of fear has descended on the research community”. (The Washington Post | 4 min read)

Reference: Open letter

Features & opinion

“The race for critical minerals, and its many side effects, illustrates how the struggle to provide public goods to the global market must restart at the local level,” argues economist Rabah Arezki. The push by big economies to secure their own supplies is incentivizing environmental damage and contributing to conflicts, displacement and the use of child labour in the countries where mining is done. “A balance must be struck so that countries rich in critical minerals get their fair share of revenues from extraction by multinational corporations,” writes Arezki. “That starts with transparent mining contracts and by strengthening local governments’ capacities to negotiate fair deals.”

Nature | 5 min read

Unicorn slippers in space takes the story of Hamlet, smooshes it into flash form with abundant liberties, and rockets Hamlet to space wearing plush unicorn slippers,” says author Katie Cervenec of the latest short story for Nature’s Futures series.

Nature | 6 min read

Researchers have developed a prototype pacemaker that fits inside a syringe and dissolves when no longer needed. It requires no external power and is controlled using light shone through the skin. The tiny pacemaker has shown promise in animal and heart models, and the team think it could also be used in other situations where electrical stimulation is needed, such as in the brain.

Nature Podcast | 37 min listen

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Image of the week

Close up on a blue and black praying mantis perched on the end of a tendril like protrusion from an orange fungus

Credit: Irina Petrova Adamatzky/World Nature Photography Awards

This eerie but vibrant snap shows a flower mantis (Creobroter sp.) perched on top of the strange fruiting body of a Cordyceps fungus. In daylight, this insect is usually green, but wildlife photographer Irina Petrova Adamatzky used strategically placed coloured lights to accentuate its otherworldly appearance and that of the fungus. The shot won a bronze award in the 2025 World Nature Photography Awards. (Nature | Leisurely scroll)

See a selection of other winning entries and more of the month’s sharpest science shots, selected by Nature’s photo team. (Irina Petrova Adamatzky/World Nature Photography Awards)

QUOTE OF THE DAY

Michael Roth, the president of Wesleyan University in Connecticut, considers how US academic leaders should respond to the Trump administration’s attack on higher education. (The New Yorker | 15 min read)

This week our penguin-seeking puzzle brings us to the stunning moss-covered banks of Coal Creek in the Coeur d’ Alene National Forest in Idaho. Can you find Leif Penguinson?

The answer will be in Monday’s e-mail, all thanks to Briefing photo editor and penguin wrangler Tom Houghton.

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Flora Graham, senior editor, Nature Briefing

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