March Madness is upon us for the 2025-26 college basketball season! The NCAA men’s basketball tournament selection committee has finalized the bracket and CBS is unveiling every matchup in the First Four and the first round. We’ve provided the full list of matchups below and added in opening odds as FanDuel Sportsbook made them available.
We’ll see considerable early movement, so we’re getting the lines in as quickly as possible. Many of the lines you’ll see listed below will change by the time you read this article, but this will help you get a handle on the line movement.
The tournament opens with the First Four on Tuesday, March 17 and Wednesday, March 18. The first round then kicks off on Thursday, March 19. The national champion will be crowned on April 6 at Lucas Oil Stadium in Indianapolis.
#11 NC State vs. #11 Texas
Point spread: Texas -1.5
Total: 163.5
Moneyline: Texas -114, NC State -105
Point spread: UMBC -1.5
Total: 142.5
Moneyline: UMBC -120, Howard +100
Point spread: SMU -7.5
Total: 165.5
Moneyline: SMU -335, Miami (OH) +265
#16 Prairie View A&M vs. #16 Lehigh
Point spread: Lehigh -1.5
Total: 146.5
Moneyline: Lehigh -120, Prairie View A&M +100
#1 Florida vs. #16 Prairie View A&M or Lehigh
Point spread: TBD
Total: TBD
Moneyline: TBD
Point spread: Iowa -2.5
Total: 131.5
Moneyline: Iowa -137, Clemson +114
#5 Vanderbilt vs. #12 McNeese
Point spread: Vanderbilt -10.5
Total: 148.5
Moneyline: Vanderbilt -710, McNeese +490
Point spread: Nebraska -13.5
Total: 136.5
Moneyline: Nebraska -1050, Troy +660
#6 North Carolina vs. #11 VCU
Point spread: UNC -2.5
Total: 156.5
Moneyline: UNC -144, VCU +120
Point spread: Illinois -22.5
Total: 149.5
Moneyline: Illinois -4500, Penn +1600
#7 Saint Mary’s vs. #10 Texas A&M
Point spread: Saint Mary’s -1.5
Total: 147.5
Moneyline: Saint Mary’s -140, Texas A&M +116
Point spread: Houston -22.5
Total: 136.5
Moneyline: Houston -8000, Idaho +2000
Point spread: Duke -27.5
Total: 136.5
Moneyline: Duke -30000, Siena +4000
Point spread: OSU -2.5
Total: 145.5
Moneyline: OSU -152, TCU +126
#5 St. John’s vs. #12 Northern Iowa
Point spread: St. John’s -10.5
Total: 132.5
Moneyline: St. John’s -410, NIU +315
#4 Kansas vs. #13 Cal Baptist
Point spread: Kansas -14.5
Total: 136.5
Moneyline: Kansas -1100, Cal Baptist +680
#6 Louisville vs. #11 South Florida
Point spread: Louisville -6.5
Total: 163.5
Moneyline: Louisville -255, USF +205
#3 Michigan State vs. #14 North Dakota State
Point spread: MSU -16.5
Total: 143.5
Moneyline: MSU -1600, NDSU +860
Point spread: UCLA -5.5
Total: 154.5
Moneyline: UCLA -230, UCF +188
Point spread: UConn -19.5
Total: 137.5
Moneyline: UConn -4500, Furman +1600
Point spread: TBD
Total: TBD
Moneyline: TBD
Point spread: Georgia -1.5
Total: 170.5
Moneyline: Georgia -137, Saint Louis +114
Point spread: Texas Tech -8.5
Total: 155.5
Moneyline: TT -275, Akron +220
Point spread: Alabama -12.5
Total: 161.5
Moneyline: Alabama -820, Hofstra +550
Point spread: TBD
Total: TBD
Moneyline: TBD
Point spread: Virginia -17.5
Total: 145.5
Moneyline: Virginia -2500, Wright State +1100
Point spread: Kentucky -3.5
Total: 161.5
Moneyline: Kentucky -142, Santa Clara +118
Point spread: Iowa State -24.5
Total: 149.5
Moneyline: USU -7000, TSU +2000
Point spread: Arizona -29.5
Total: 152.5
Moneyline: Arizona -50000, LIU +5500
Point spread: Utah State -1.5
Total: 147.5
Moneyline: Utah State -126, Villanova +104
Point spread: Wisconsin -11.5
Total: 166.5
Moneyline: Wisconsin -610, High Point +440
Point spread: Arkansas -15.5
Total: 160.5
Moneyline: Arkansas -1300, Hawai’i +760
Point spread: TBD
Total: TBD
Moneyline: TBD
Point spread: Gonzaga -18.5
Total: 159.5
Moneyline: Gonzaga -3500, Kennesaw State +1280
Point spread: Miami -2.5
Total: 150.5
Moneyline: Miami -130, Missouri +108
Point spread: Purdue -22.5
Total: 163.5
Moneyline: Purdue -8000, Queens +2200
