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HomeNatureAncient DNA reveals the prehistory of the Uralic and Yeniseian peoples

Ancient DNA reveals the prehistory of the Uralic and Yeniseian peoples

  • Janhunen, J. Proto-Uralic—what, where, and when? Quasquicentennial Finno Ugrian Soc. 258, 57–78 (2009).


    Google Scholar
     

  • Tambets, K. et al. Genes reveal traces of common recent demographic history for most of the Uralic-speaking populations. Genome Biol. 19, 139 (2018).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lamnidis, T. C. et al. Ancient Fennoscandian genomes reveal origin and spread of Siberian ancestry in Europe. Nat. Commun. 9, 5018 (2018).

    Article 
    ADS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Saag, L. et al. The arrival of Siberian ancestry connecting the Eastern Baltic to Uralic speakers further east. Curr. Biol. 29, 1701–1711.e16 (2019).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Vajda, E. Dene-Yeniseian. Diachronica 35, 277–295 (2018).

    Article 

    Google Scholar
     

  • Reich, D. et al. Reconstructing Native American population history. Nature 488, 370–374 (2012).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Flegontov, P. et al. Palaeo-Eskimo genetic ancestry and the peopling of Chukotka and North America. Nature 570, 236–240 (2019).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Sikora, M. et al. The population history of northeastern Siberia since the Pleistocene. Nature 570, 182–188 (2019).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Nielsen, S. V. et al. Bayesian inference of admixture graphs on Native American and Arctic populations. PLoS Genet. 19, e1010410 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Flegontov, P. et al. Genomic study of the Ket: a Paleo-Eskimo-related ethnic group with significant ancient North Eurasian ancestry. Sci. Rep. 6, 20768 (2016).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Jeong, C. et al. The genetic history of admixture across inner Eurasia. Nat Ecol. Evol. 3, 966–976 (2019).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kidd, K. K. et al. North Asian population relationships in a global context. Sci. Rep. 12, 7214 (2022).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Svyatko, S. V. et al. Freshwater reservoir effects in archaeological contexts of Siberia and the Eurasian Steppe. Radiocarbon 64, 377–388 (2022).

    Article 
    CAS 

    Google Scholar
     

  • Zhang, F. et al. The genomic origins of the Bronze Age Tarim Basin mummies. Nature 599, 256–261 (2021).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kılınç, G. M. et al. Human population dynamics and Yersinia pestis in ancient northeast Asia. Sci. Adv. 7, eabc4587 (2021).

    Article 
    ADS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Yu, H. et al. Paleolithic to Bronze Age Siberians reveal connections with first Americans and across Eurasia. Cell 181, 1232–1245.e20 (2020).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Harney, É., Patterson, N., Reich, D. & Wakeley, J. Assessing the performance of qpAdm: a statistical tool for studying population admixture. Genetics 217, iyaa045 (2021).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Flegontova, O. et al. Performance of qpAdm-based screens for genetic admixture on graph-shaped histories and stepping-stone landscapes. Genetics 230, iyaf047 (2025).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Davidson, R. et al. Allelic bias when performing in-solution enrichment of ancient human DNA. Mol. Ecol. Resour. 23, 1823–1840 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Grebenyuk, P. S., Fedorchenko, A. Y., Dyakonov, V. M., Lebedintsev, A. I. & Malyarchuk, B. A. in Humans in the Siberian Landscapes: Ethnocultural Dynamics and Interaction with Nature and Space (eds Bocharnikov, V. N. & Steblyanskaya, A. N.) 89–133 (Springer, 2022).

  • Yang, M. A. et al. Ancient DNA indicates human population shifts and admixture in northern and southern China. Science 369, 282–288 (2020).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar
     

  • Mao, X. et al. The deep population history of northern East Asia from the Late Pleistocene to the Holocene. Cell 184, 3256–3266.e13 (2021).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Moreno-Mayar, J. V. et al. Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans. Nature 553, 203–207 (2018).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar
     

  • Mathieson, I. et al. The genomic history of southeastern Europe. Nature 555, 197–203 (2018).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Haak, W. et al. Massive migration from the steppe was a source for Indo-European languages in Europe. Nature 522, 207–211 (2015).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Raghavan, M. et al. Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans. Nature 505, 87–91 (2014).

    Article 
    ADS 
    PubMed 

    Google Scholar
     

  • de Barros Damgaard, P. et al. The first horse herders and the impact of early Bronze Age steppe expansions into Asia. Science 360, eaar7711 (2018).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Saag, L. et al. Genetic ancestry changes in Stone to Bronze Age transition in the East European plain. Sci. Adv. 7, eabd6535 (2021).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Narasimhan, V. M. et al. The formation of human populations in South and Central Asia. Science 365, eaat7487 (2019).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Posth, C. et al. Palaeogenomics of Upper Palaeolithic to Neolithic European hunter-gatherers. Nature 615, 117–126 (2023).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Allentoft, M. E. et al. Population genomics of Bronze Age Eurasia. Nature 522, 167–172 (2015).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar
     

  • de Barros Damgaard, P. et al. 137 ancient human genomes from across the Eurasian steppes. Nature 557, 369–374 (2018).

    Article 
    ADS 

    Google Scholar
     

  • Krzewińska, M. et al. Ancient genomes suggest the eastern Pontic-Caspian steppe as the source of western Iron Age nomads. Sci. Adv. 4, eaat4457 (2018).

    Article 
    ADS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Järve, M. et al. Shifts in the genetic landscape of the Western Eurasian Steppe associated with the beginning and end of the Scythian dominance. Curr. Biol. 29, 2430–2441.e10 (2019).

    Article 
    PubMed 

    Google Scholar
     

  • Wei, L.-H. et al. Paternal origin of Paleo-Indians in Siberia: insights from Y-chromosome sequences. Eur. J. Hum. Genet. 26, 1687–1696 (2018).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Karmin, M. et al. A recent bottleneck of Y chromosome diversity coincides with a global change in culture. Genome Res. 25, 459–466 (2015).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • YFull. ISOGG Wiki https://isogg.org/wiki/YFull (2024).

  • Pakendorf, B. et al. Investigating the effects of prehistoric migrations in Siberia: genetic variation and the origins of Yakuts. Hum. Genet. 120, 334–353 (2006).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Chernykh, E. N. & Kuz’minykh, S. V. Drevnyaya metallurgiya Severnoy Evrazii (Seiminsko-Turbinskiy fenomen) (Nauka, 1989).

  • Marchenko, Z. V., Svyatko, S. V., Molodin, V. I., Grishin, A. E. & Rykun, M. P. Radiocarbon chronology of complexes with Seima-Turbino type objects (Bronze Age) in Southwestern Siberia. Radiocarbon 59, 1381–1397 (2017).

    Article 
    CAS 

    Google Scholar
     

  • Chernykh, E. N. Formation of the Eurasian ‘Steppe Belt’ of stockbreeding cultures: viewed through the prism of archaeometallurgy and radiocarbon dating. Archaeol. Ethnol. Anthropol. Eurasia 35, 36–53 (2008).

    Article 

    Google Scholar
     

  • Meicun, L. & Liu, X. The origins of metallurgy in China. Antiquity 91, e6 (2017).

    Article 

    Google Scholar
     

  • Chernykh, E. N. in Nomadic Cultures in the Mega-Structure of the Eurasian World (eds Savinetskaya, I & Hommel, P. N.) 234–249 (Academic Studies, 2017).

  • Molodin, V. I., Durakov, I. A., Mylnikova, L. N. & Nesterova, M. S. The adaptation of the Seima-Turbino tradition to the Bronze Age cultures in the south of the West Siberian plain. Archaeol. Ethnol. Anthropol. Eurasia 46, 49–58 (2018).

    Article 

    Google Scholar
     

  • Ilumäe, A.-M. et al. Human Y chromosome haplogroup N: a non-trivial time-resolved phylogeography that cuts across language families. Am. J. Hum. Genet. 99, 163–173 (2016).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kuzminykh, S. V. Seima-Turbino transcultural phenomenon: migration or diffusion of technology. In Mobility and Migration: Concepts, Methods, Results: Programme and Abstracts of the V International Scientific Symposium (eds Molodin, V. I. & Hansen, S.) 52–56 (2019).

  • Makarov, N. P. Khronologiya i periodizatsiya epokhi Neolita i Bronzy Krasnoyarskoy lesostepi [The chronology and periodization of the Neolithic and Bronze Krasnoyarsk forest]. Izv. Lab. Drevn. Tekhnol. 1, 149–171 (2005).


    Google Scholar
     

  • Childebayeva, A. et al. Bronze age Northern Eurasian genetics in the context of development of metallurgy and Siberian ancestry. Commun. Biol. 7, 723 (2024).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kristiansen, K. The Rise of Bronze Age Peripheries and the Expansion of International Trade 1950–1100 bc. Trade and Civilisation Cambridge (eds Kristiansen, K. et al.) 87–112 (Cambridge Univ. Press, 2018).

  • Powell, W. et al. Tin from Uluburun shipwreck shows small-scale commodity exchange fueled continental tin supply across Late Bronze Age Eurasia. Sci. Adv. 8, eabq3766 (2022).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Singh, M. & Glowacki, L. Human social organization during the Late Pleistocene: Beyond the nomadic-egalitarian model. Evol. Hum. Behav. 43, 418–431 (2022).

    Article 

    Google Scholar
     

  • Tarasov, A. & Nordqvist, K. Made for exchange: the Russian Karelian lithic industry and hunter-fisher-gatherer exchange networks in prehistoric north-eastern Europe. Antiquity 96, 34–50 (2022).

    Article 

    Google Scholar
     

  • Piezonka, H. et al. The world’s oldest-known promontory fort: Amnya and the acceleration of hunter-gatherer diversity in Siberia 8000 years ago. Antiquity 97, 1381–1401 (2023).

    Article 

    Google Scholar
     

  • Holopainen, S. Indo-Iranian Borrowings in Uralic: Critical Overview of Sound Substitutions and Distribution Criterion. Doctoral thesis, Univ. of Helsinki (2019).

  • Grünthal, R. et al. Drastic demographic events triggered the Uralic spread. Diachronica 39, 490–524 (2022).

    Article 

    Google Scholar
     

  • Gnecchi-Ruscone, G. A. et al. Ancient genomic time transect from the Central Asian Steppe unravels the history of the Scythians. Sci. Adv. 7, eabe4414 (2021).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kumar, V. et al. Genetic continuity of Bronze Age ancestry with increased Steppe-related ancestry in Late Iron Age Uzbekistan. Mol. Biol. Evol. 38, 4908–4917 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Guarino-Vignon, P., Marchi, N., Bendezu-Sarmiento, J., Heyer, E. & Bon, C. Genetic continuity of Indo-Iranian speakers since the Iron Age in southern Central Asia. Sci. Rep. 12, 733 (2022).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kovtun, I. V. Predystoriya Indoariyskoy Mifologii (Aziya-Print, 2013).

  • Häkkinen, J. in Iter Polyphonicum Multilinguae (eds Hyytiäinen, T. et al.) 91–101 (2012).

  • Buchhorn, M. et al. Copernicus Global Land Service: land cover 100m: collection 3: epoch 2019: Globe (V3.0.1) [Data set]. Zenodo https://doi.org/10.5281/zenodo.3939050 (2020).

  • Rohland, N., Glocke, I., Aximu-Petri, A. & Meyer, M. Extraction of highly degraded DNA from ancient bones, teeth and sediments for high-throughput sequencing. Nat. Protoc. 13, 2447–2461 (2018).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Dabney, J. et al. Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments. Proc. Natl Acad. Sci. USA 110, 15758–15763 (2013).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Briggs, A. W. & Heyn, P. in Ancient DNA. Methods in Mol. Biol. (eds Shapiro, B. & Hofreiter, M.) https://doi.org/10.1007/978-1-61779-516-9_18 (2012).

  • Rohland, N., Harney, E., Mallick, S., Nordenfelt, S. & Reich, D. Partial uracil–DNA–glycosylase treatment for screening of ancient DNA. Phil. Trans. R. Soc. B 370, 20130624 (2015).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Gansauge, M.-T., Aximu-Petri, A., Nagel, S. & M MEYER, Manual and automated preparation of single-stranded DNA libraries for the sequencing of DNA from ancient biological remains and other sources of highly degraded DNA. Nat. Protoc. 15, 2279–2300 (2020).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Fu, Q. et al. An early modern human from Romania with a recent Neanderthal ancestor. Nature 524, 216–219 (2015).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Maricic, T., Whitten, M. & Pääbo, S. Multiplexed DNA sequence capture of mitochondrial genomes using PCR products. PLoS ONE 5, e14004 (2010).

    Article 
    ADS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Speir, M. L. et al. The UCSC Genome Browser Database: 2016 update. Nucleic Acids Res. 44, D717–D725 (2016).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Li, H. & Durbin, R. Fast and accurate long-read alignment with Burrows–Wheeler transform. Bioinformatics 26, 589–595 (2010).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Behar, D. M. et al. A “Copernican” reassessment of the human mitochondrial DNA tree from its root. Am. J. Hum. Genet. 90, 675–684 (2012).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Fu, Q. et al. A revised timescale for human evolution based on ancient mitochondrial genomes. Curr. Biol. 23, 553–559 (2013).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Korneliussen, T. S., Albrechtsen, A. & Nielsen, R. ANGSD: analysis of next generation sequencing data. BMC Bioinformatics 15, 356 (2014).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Weissensteiner, H. et al. HaploGrep 2: mitochondrial haplogroup classification in the era of high-throughput sequencing. Nucleic Acids Res. 44, W58–W63 (2016).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lazaridis, I. et al. The genetic history of the Southern Arc: a bridge between West Asia and Europe. Science 377, eabm4247 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Alexander, D. H., Novembre, J. & Lange, K. Fast model-based estimation of ancestry in unrelated individuals. Genome Res. 19, 1655–1664 (2009).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Purcell, S. et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559–575 (2007).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Patterson, N., Price, A. L. & Reich, D. Population structure and eigenanalysis. PLoS Genet. 2, e190 (2006).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Patterson, N. et al. Ancient admixture in human history. Genetics 192, 1065–1093 (2012).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Maier, R., Flegontov, P., Flegontova, O., Işıldak, U., Changmai, P. & Reich, D. On the limits of fitting complex models of population history to f-statistics. eLife 12, e85492 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kennett, D. J. et al. Archaeogenomic evidence reveals prehistoric matrilineal dynasty. Nat. Commun. 8, 14115 (2017).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Van de Loosdrecht, M. et al. Pleistocene North African genomes link near Eastern and sub-Saharan African human populations. Science 360, 548–552 (2018).

    Article 
    ADS 
    PubMed 

    Google Scholar
     

  • Olalde, I. et al. The genomic history of the Iberian Peninsula over the past 8000 years. Science 363, 1230–1234 (2019).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Monroy Kuhn, J. M., Jakobsson, M. & Günther, T. Estimating genetic kin relationships in prehistoric populations. PLoS ONE 13, e0195491 (2018).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

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