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HomeNatureAlternating high-fat diet enhances atherosclerosis by neutrophil reprogramming

Alternating high-fat diet enhances atherosclerosis by neutrophil reprogramming

  • Libby, P. The changing landscape of atherosclerosis. Nature 592, 524–533 (2021).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar
     

  • Strohacker, K., Carpenter, K. C. & McFarlin, B. K. Consequences of weight cycling: an increase in disease risk? Int. J. Exerc. Sci. 2, 191–201 (2009).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zezulin, A. U. et al. RUNX1 is required in granulocyte-monocyte progenitors to attenuate inflammatory cytokine production by neutrophils. Genes Dev. 37, 605–620 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Roth, G. A. et al. Global burden of cardiovascular diseases and risk factors, 1990-2019: update from the GBD 2019 study. J. Am. Coll. Cardiol. 76, 2982–3021 (2020).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Silvestre-Roig, C., Braster, Q., Ortega-Gomez, A. & Soehnlein, O. Neutrophils as regulators of cardiovascular inflammation. Nat. Rev. Cardiol. 17, 327–340 (2020).

    Article 
    PubMed 

    Google Scholar
     

  • Zadelaar, S. et al. Mouse models for atherosclerosis and pharmaceutical modifiers. Arterioscler. Thromb. Vasc. Biol. 27, 1706–1721 (2007).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Giral, P., Neumann, A., Weill, A. & Coste, J. Cardiovascular effect of discontinuing statins for primary prevention at the age of 75 years: a nationwide population-based cohort study in France. Eur. Heart J. 40, 3516–3525 (2019).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Bekkering, S. et al. Oxidized low-density lipoprotein induces long-term proinflammatory cytokine production and foam cell formation via epigenetic reprogramming of monocytes. Arterioscler. Thromb. Vasc. Biol. 34, 1731–1738 (2014).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Christ, A. et al. Western diet triggers NLRP3-dependent innate immune reprogramming. Cell 172, 162–175 (2018).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Riksen, N. P., Bekkering, S., Mulder, W. J. M. & Netea, M. G. Trained immunity in atherosclerotic cardiovascular disease. Nat. Rev. Cardiol. 20, 799–811 (2023).

    Article 
    PubMed 

    Google Scholar
     

  • Tang, W. H. W., Li, D. Y. & Hazen, S. L. Dietary metabolism, the gut microbiome, and heart failure. Nat. Rev. Cardiol. 16, 137–154 (2019).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Depommier, C. et al. Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study. Nat. Med. 25, 1096–1103 (2019).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Stoeckius, M. et al. Simultaneous epitope and transcriptome measurement in single cells. Nat. Methods 14, 865–868 (2017).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Capucetti, A., Albano, F. & Bonecchi, R. Multiple roles for chemokines in neutrophil biology. Front. Immunol. 11, 1259 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Mitroulis, I. et al. Modulation of myelopoiesis progenitors is an integral component of trained immunity. Cell 172, 147–161 (2018).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Boettcher, S. et al. Cutting edge: LPS-induced emergency myelopoiesis depends on TLR4-expressing nonhematopoietic cells. J. Immunol. 188, 5824–5828 (2012).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Pietras, E. M. et al. Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal. Nat. Cell Biol. 18, 607–618 (2016).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Al-Rifai, R. et al. JAK2V617F mutation drives vascular resident macrophages toward a pathogenic phenotype and promotes dissecting aortic aneurysm. Nat. Commun. 13, 6592 (2022).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Coll, R. C. et al. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat. Med. 21, 248–255 (2015).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Combadiere, C. et al. Combined inhibition of CCL2, CX3CR1 and CCR5 abrogates Ly6Chi and Ly6Clo monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice. Circulation 117, 1649–1657 (2008).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Luo, J., Thomassen, J. Q., Nordestgaard, B. G., Tybjaerg-Hansen, A. & Frikke-Schmidt, R. Neutrophil counts and cardiovascular disease. Eur. Heart J. 44, 4953–4964 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Soehnlein, O. Multiple roles for neutrophils in atherosclerosis. Circ. Res. 110, 875–888 (2012).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kalafati, L. et al. Innate immune training of granulopoiesis promotes anti-tumor activity. Cell 183, 771–785 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Moorlag, S. et al. BCG vaccination induces long-term functional reprogramming of human neutrophils. Cell Rep. 33, 108387 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Warnatsch, A., Ioannou, M., Wang, Q. & Papayannopoulos, V. Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis. Science 349, 316–320 (2015).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Valles, J. et al. Neutrophil extracellular traps are increased in patients with acute ischemic stroke: prognostic significance. Thromb. Haemost. 117, 1919–1929 (2017).

    Article 
    PubMed 

    Google Scholar
     

  • Tedgui, A. & Mallat, Z. Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol. Rev. 86, 515–581 (2006).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Rohde, D. et al. Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease. Nat Cardiovasc. Res. 1, 28–44 (2022).

    Article 
    PubMed 

    Google Scholar
     

  • Noz, M. P. et al. Reprogramming of bone marrow myeloid progenitor cells in patients with severe coronary artery disease. eLife 9, e60939 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Schultze, J. L., Mass, E. & Schlitzer, A. Emerging principles in myelopoiesis at homeostasis and during infection and inflammation. Immunity 50, 288–301 (2019).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Bellissimo, D. C. & Speck, N. A. RUNX1 mutations in inherited and sporadic leukemia. Front. Cell Dev. Biol. 5, 111 (2017).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Bellissimo, D. C. et al. Runx1 negatively regulates inflammatory cytokine production by neutrophils in response to Toll-like receptor signaling. Blood Adv. 4, 1145–1158 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Boettcher, S. & Manz, M. G. Regulation of inflammation- and infection-driven hematopoiesis. Trends Immunol. 38, 345–357 (2017).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Deon, D. et al. Cross-talk between IL-1 and IL-6 signaling pathways in rheumatoid arthritis synovial fibroblasts. J. Immunol. 167, 5395–5403 (2001).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Ridker, P. M. et al. Antiinflammatory therapy with canakinumab for atherosclerotic disease. N. Engl. J. Med. 377, 1119–1131 (2017).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Febbraio, M. et al. A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. J. Biol. Chem. 274, 19055-62 (1999).

  • Olofsen, P. A. et al. Effective, long-term, neutrophil depletion using a murinized anti-Ly-6G 1A8 antibody. Cells 11, 3406 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Ait-Oufella, H. et al. B cell depletion reduces the development of atherosclerosis in mice. J. Exp. Med. 207, 1579–1587 (2010).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Rizzo, G. et al. Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction. Cardiovasc. Res. https://doi.org/10.1093/cvr/cvac113 (2022).

  • Stuart, T. et al. Comprehensive integration of single-cell data. Cell 177, 1888–1902 (2019).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Korsunsky, I. et al. Fast, sensitive and accurate integration of single-cell data with Harmony. Nat. Methods 16, 1289–1296 (2019).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zernecke, A. et al. Integrated single-cell analysis based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis. Cardiovasc. Res. https://doi.org/10.1093/cvr/cvac161 (2022).

  • Hao, Y. et al. Integrated analysis of multimodal single-cell data. Cell 184, 3573–3587 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Germain, P. L., Lun, A., Garcia Meixide, C., Macnair, W. & Robinson, M. D. Doublet identification in single-cell sequencing data using scDblFinder. F1000Res. 10, 979 (2021).

    Article 
    PubMed 

    Google Scholar
     

  • Sokol, H. et al. Fungal microbiota dysbiosis in IBD. Gut 66, 1039–1048 (2017).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Schmieder, R. & Edwards, R. Quality control and preprocessing of metagenomic datasets. Bioinformatics 27, 863–864 (2011).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Bolyen, E. et al. Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2. Nat. Biotechnol. 37, 852–857 (2019).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Callahan, B. J. et al. DADA2: high-resolution sample inference from Illumina amplicon data. Nat. Methods 13, 581–583 (2016).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Quast, C. et al. The SILVA ribosomal RNA gene database project: improved data processing and web-based tools. Nucleic Acids Res. 41, D590–D596 (2013).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • McMurdie, P. J. & Holmes, S. phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data. PLoS ONE 8, e61217 (2013).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Segata, N. et al. Metagenomic biomarker discovery and explanation. Genome Biol. 12, R60 (2011).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

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