Broad Institute of MIT and Harvard, Cambridge, MA, USA
Tim H. H. Coorens, Boxun Zhao, Adam Voshall, Kristin G. Ardlie, Bradley E. Bernstein, Jason D. Buenrostro, Kathleen H. Burns, Fei Chen, Sangita Choudhury, Gad Getz, Niall J. Lennon, Po-Ru Loh, Pradeep Natarajan, Christopher A. Walsh, Eunjung Alice Lee, Kristin G. Ardlie, Viktor Adalsteinsson, Lisa Anderson, Carrie Cibulskis, Laura Domènech, Kiran Garimella, Whitney Hornsby, Steve Huang, Satoshi Koyama, Niall J. Lennon, Tetsushi Nakao, Azeet Narayan, Constantijn Scharlee, Md Mesbah Uddin, Liying Xue, Zhi Yu, Shadi Zaheri, Ruolin Liu, Ning Stella Li, Hang Su, Guanlan Dong, Nazia Hilal, Shayna L. Mallett, Julia Markowski, Justin S. Becker, Aidan H. Burn, Wen-Chih Cheng, Jennifer A. Karlow, Cheuk-Ting Law, Shayna L. Mallet, Carlos Mendez-Dorantes, Khue H. Nguyen, Adam Voshall, Boxun Zhao, Benno Orr & Andrew J. C. Russell
Department of Anatomy, Yonsei University College of Medicine, Seoul, Korea
Ji Won Oh, Yujin Angelina Choi, Nam Seop Lim, Geon Hue Bae, Areum Cho, June Hyug Choi, Hyungbin Chun, Seok-Won Jeong, Su Rim Kim, Seong Gyu Kwon, Soung-Hoon Lee, Nanda Maya Mali, Jung Min Park, JaeEun Shin, Saravanan Ganesan & Ivan Raimondi
Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Korea
Ji Won Oh, Nam Seop Lim, Geon Hue Bae, Areum Cho, June Hyug Choi, Hyungbin Chun, Seok-Won Jeong, Min Ji, Mee Sook Jun, Su Rim Kim, Seong Gyu Kwon, Soung-Hoon Lee, Nanda Maya Mali, Jung Min Park & JaeEun Shin
Division of Genetics and Genomics, Boston Children’s Hospital, Boston, MA, USA
Boxun Zhao, Adam Voshall, Sangita Choudhury, Diane D. Shao, Christopher A. Walsh, Eunjung Alice Lee, Mingyun Bae, Junseok Park, Suenghyun Wang, Xi Zeng, Guanlan Dong, Nazia Hilal, Se-Young Jo, Shayna L. Mallett, Monica Devi Manam, Shulin Mao, Christopher Walsh, Sijing Zhao, Mee Sook Jun, Emre Caglayan, Hayley Cline, Shelbi E. Gill, Robert Sean Hill, Andrea J. Kriz, Alisa Mo, Daniel Snellings, Shayna L. Mallet, Khue H. Nguyen, Adam Voshall & Boxun Zhao
Manton Center for Orphan Disease Research, Boston Children’s Hospital, Boston, MA, USA
Boxun Zhao, Adam Voshall, Christopher A. Walsh, Eunjung Alice Lee, Mingyun Bae, Junseok Park, Xi Zeng, Shayna L. Mallet, Khue H. Nguyen, Adam Voshall & Boxun Zhao
Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Boxun Zhao, Adam Voshall, Sangita Choudhury, Diane D. Shao, Christopher A. Walsh, Eunjung Alice Lee, Suenghyun Wang, Guanlan Dong, Nazia Hilal, Se-Young Jo, Shayna L. Mallett, Monica Devi Manam, Shulin Mao, Christopher Walsh, Sijing Zhao, Emre Caglayan, Hayley Cline, Shelbi E. Gill, Robert Sean Hill, Andrea J. Kriz, Alisa Mo & Daniel Snellings
Department of Quantitative Health Sciences, Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA
Alexej Abyzov, Taejeong Bae, Mrunal Dehankar, Yeongjun Jang, Arijit Panda & Milovan Suvakov
McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA
Lucinda Antonacci-Fulton, Ting Wang, Casey Andrews, Sarah Cody, Milinn Kremitzki, Tina Lindsay, Derek Albracht, Eddie Belter, Emma Casey, Yuchen Cheng, Shihua Dong, Qichen Fu, Robert Fulton, John Garza, Sheng Chih Jin, Nahyun Kong, Zefan Li, Shane Liu, Juan F. Macias-Velasco, Elvisa Mehinovic, Benpeng Miao, Purva Patel, Andrew Ruttenberg, Jiawei Shen, Zitian Tang, Chad Tomlinson, Wenjin Zhang & Zilan Xin
Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada
Samuel Aparicio
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada
Samuel Aparicio
New York Genome Center, New York, NY, USA
Samuel Aparicio, Soren Germer, Dan A. Landau, Rahul Satija, Jade E. B. Carter, William Driscoll, Uday S. Evani, Heather Geiger, M. Tausif Hasan, Manisha Kher, Rajeeva Musunuri, Giuseppe Narzisi, Nicolas Robine, Alexi Runnels, Sammantha Avaylon, Alexandre Pellan Cheng, Andrew R. D’Avino, Husain Danish, Elliot Eton, Foteini Fotopoulo, Saravanan Ganesan, Yiyun Lin, Qing Luo, Levan Mekerishvili, Joe Pelt, Catherine Potenski, Tamara Prieto, Jake Qiu, Ivan Raimondi, Mandeep Singh, Dennis Yuan & John Zinno
National Disease Research Interchange, Philadelphia, PA, USA
Thomas J. Bell, Melissa W. VonDran, Valerie J. Estela-Pro, Azra Hasan, M. Kathryn Leonard & Isabel Sleeman
Center for Developmental Biology and Regenerative Medicine, Seattle Children’s Research Institute, Seattle, WA, USA
James T. Bennett, Dana M. Jensen, Kelsey Loy, Jeffrey Ou, Nancy L. Parmalee, Meranda M. Pham, Lila Sutherlin, Natalie Y. T. Au & Amy Leonardson
Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, WA, USA
James T. Bennett
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Bradley E. Bernstein & Justin S. Becker
Department of Pathology, Harvard Medical School, Boston, MA, USA
Bradley E. Bernstein, Kathleen H. Burns, Gad Getz, Justin S. Becker, Aidan H. Burn, Wen-Chih Cheng, Jennifer A. Karlow, Cheuk-Ting Law & Carlos Mendez-Dorantes
Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA
Thomas G. Blanchard
Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA
Alan P. Boyle, Ryan E. Mills, Brandt A. Bessell, Ingrid Flashpohler, Steve Losh, Torrin L. McDonald, Jessica A. Switzenberg, Jinhao Wang & Weichen Zhou
Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA
Alan P. Boyle, Ryan E. Mills & Camille Mumm
Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA
Jason D. Buenrostro, Fei Chen & Andrew J. C. Russell
Department of Pathology, Dana-Farber Cancer Institute, Boston, MA, USA
Kathleen H. Burns, Aidan H. Burn, Wen-Chih Cheng, Jennifer A. Karlow, Cheuk-Ting Law & Carlos Mendez-Dorantes
Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA
Rui Chen, Harsha V. Doddapaneni, Richard A. Gibbs, Fritz J. Sedlazeck, Sravya Bhamidipati, Hsu Chao, Christopher M. Grochowski, Harsha V. Doddapaneni, Divya Kalra, Ziad Khan, Kavya Kottapalli, Marie-Claude Gingras, Walker Hale, Heer Mehta, Donna M. Muzny, Luis F. Paulin, Jeffrey Rogers, Evette Scott, Fritz J. Sedlazeck, Kimberly Walker, Yilei Fu, Michal B. Izydorczyk, Luis F. Paulin, Xiaomei Zhan & Xinchang Zheng
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
Rui Chen, Richard A. Gibbs, Fritz J. Sedlazeck, Tao P. Wu, Chenghang Zong, Elizabeth G. Atkinson, Muchun Niu, Jeffrey Rogers, Fritz J. Sedlazeck, Tao Wu, Jiayi Luo, Yichi Niu & Yang Zhang
Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA
Evan E. Eichler, Andrew B. Stergachis, Stephanie Bohaczuk, Colleen P. Davis, Christian D. Frazar, Kendra Hoekzema, Meng-Fan Huang, Caitlin Jacques, J. Thomas Kolar, Youngjun Kwon, Yizi Mao, Katherine M. Munson, Shane Neph, Luyao Ren, Joshua D. Smith, Melanie Sorensen, Mitchell R. Vollger, Chia-Lin Wei, Jeffrey M. Weiss, Christina Zakarian, Jiadong Lin, Taralynn Mack, Sean R. McGee, Patrick M. Nielsen, Erica Ryke, Tristan Shaffer & Elliott G. Swanson
Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA
Evan E. Eichler & Luyao Ren
Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA
Gilad D. Evrony, Benjamin Costa, Nisrine T. Jabara & Marta Grońska-Pęski
Department of Pediatrics, New York University Grossman School of Medicine, New York, NY, USA
Gilad D. Evrony, Benjamin Costa, Nisrine T. Jabara & Marta Grońska-Pęski
Department of Neuroscience and Physiology, New York University Grossman School of Medicine, New York, NY, USA
Gilad D. Evrony, Benjamin Costa, Nisrine T. Jabara & Marta Grońska-Pęski
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Melissa A. Faith
Center for Behavioral Health, Johns Hopkins All Children’s Hospital, Saint Petersburg, FL, USA
Melissa A. Faith & Phoebe McDermott
Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA
Thomas G. Fazzio, Trishita Basak & Katrina Newcomer
Department of Genetics, Washington University, St. Louis, MO, USA
Robert S. Fulton
Program in Bioinformatics and Integrative Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA
Manuel Garber, Azita Ghodssi & Yuqing Wang
Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA
Nils Gehlenborg, Heng Li, Peter J. Park, Michele Berselli, Ann Caplin, Hye-Jung Elizabeth Chun, Niklas L. Engel, William C. Feng, Yan Gao, Dominik Glodzik, Yoo-Jin Jiny Ha, Hu Jin, Sehi L’Yi, Lovelace J. Luquette, Maximilian Marin, Julia Markowski, Dominika Maziec, Huang Neng, Sarah Nicholson, Han Qu, Douglas Rioux, William Ronchetti, Andrew Schroeder, Corinne E. Sexton, Yichen Si, Alexander D. Veit, Vinayak V. Viswanadham, Kyung Ah Woo, Yuwei Zhang, Yifan Zhao, Michail Andreopoulos, Shannon Ehmsen, Cesar Ferreyra-Mansilla, Clara TaeHee Kim, David Michaels, Bianca Morris & Niklas L. Engel
Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
Gad Getz
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Raquel G. Hernandez
Center for Pediatric Health Equity Research, Johns Hopkins All Children’s Hospital, Saint Petersburg, FL, USA
Raquel G. Hernandez
Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, USA
Fulai Jin, Yan Li, He Li, Yan Li & Leina Lu
Department of Computer and Data Sciences, School of Engineering, Case Western Reserve University, Cleveland, OH, USA
Fulai Jin, He Li, Yan Li & Leina Lu
European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany
Jan O. Korbel
Bridging Research Division on Mechanisms of Genomic Variation and Data Science, German Cancer Research Center, Heidelberg, Germany
Jan O. Korbel
Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA
Dan A. Landau, Alexandre Pellan Cheng, Wei-Yu Chi, Mariela Cortés-López, Andrew R. D’Avino, Husain Danish, Elliot Eton, Foteini Fotopoulo, Yiyun Lin, Qing Luo, Levan Mekerishvili, Joe Pelt, Catherine Potenski, Tamara Prieto, Jake Qiu, Mandeep Singh, Dennis Yuan & John Zinno
Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA
Dan A. Landau
Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA
Heather A. Lawson, Ting Wang, Daofeng Li, Wenjin Zhang, Justin Chen & Daofeng Li
Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA
Heng Li, Maximilian Marin, Huang Neng, Qin Qian, Kar-Tong Tan & Ying Zhou
Division of Genetics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA
Po-Ru Loh & David Tang
Department of Human Genetics, University of Utah, Salt Lake City, UT, USA
Gabor Marth, Gabor T. Marth, Brad Demarest, Stephanie Gardiner & Stephanie J. Georges
Lieber Institute for Brain Development, Baltimore, MD, USA
Michael J. McConnell
Department of Pathology, Stanford University, Stanford, CA, USA
Stephen B. Montgomery
Department of Genetics, Stanford University, Stanford, CA, USA
Stephen B. Montgomery, Alexander E. Urban, Evin Padhi, Yiling Elaine Huang, Reenal Pattni, Carolin Purman & Bo Zhou
Department of Biomedical Data Science, Stanford University, Stanford, CA, USA
Stephen B. Montgomery
Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA
Pradeep Natarajan & Md Mesbah Uddin
Department of Medicine, Harvard Medical School, Boston, MA, USA
Pradeep Natarajan
Ludwig Center at Harvard, Harvard Medical School, Boston, MA, USA
Peter J. Park
Center for Genomics and Systems Biology, New York University, New York, NY, USA
Rahul Satija
Department of Computer Science, Rice University, Houston, TX, USA
Fritz J. Sedlazeck
Department of Neurology, Boston Children’s Hospital, Boston, MA, USA
Diane D. Shao
Department of Epigenetics, Van Andel Institute, Grand Rapids, MI, USA
Hui Shen, H. Josh Jang, Benjamin K. Johnson, Theron Palmer, Mary F. Majewski, Daniel C. Rohrer & Ayush Semwal
Brotman Baty Institute for Precision Medicine, Seattle, WA, USA
Andrew B. Stergachis
Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA, USA
Andrew B. Stergachis, Min-Hwan Sohn, Jane Ranchalis, Adriana E. Sedeño-Cortés, Anna Minkina, Chris Oliveira & Elliott G. Swanson
Division of Medical Genetics, Department of Pediatrics, University of Utah, Salt Lake City, UT, USA
Hunter R. Underhill & Yingqi Zhang
Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA
Hunter R. Underhill
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
Alexander E. Urban
Howard Hughes Medical Institute, Boston, MA, USA
Christopher A. Walsh & Christopher Walsh
Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine, St. Louis, MO, USA
Ting Wang
Roy M. and Phyllis Gough Huffington Center on Aging, Baylor College of Medicine, Houston, TX, USA
Tao P. Wu
Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA
Tao P. Wu & Chenghang Zong
Child Study Center, Yale University, New Haven, CT, USA
Flora M. Vaccarino & Abhiram Natu
Department of Neuroscience, Yale University, New Haven, CT, USA
Flora M. Vaccarino
Yale Stem Cell Center, Yale University, New Haven, CT, USA
Flora M. Vaccarino
Office of Strategic Coordination, Division of Program Coordination, Planning, and Strategic Initiatives, National Institutes of Health, Bethesda, MD, USA
Richard S. Conroy, Brionna Y. Hair & Dena C. Procaccini
National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
Walter J. Koroshetz & Jill A. Morris
Division of Neuroscience and Behavior, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA
Roger Little & Amy C. Lossie
Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
Wendy Wang
ConnectLife, Williamsville, NY, USA
Kayla Giancarlo, Melissa Grimm & Mary Pfeiffer
The Northwest Genomics Center, University of Washington, Seattle, WA, USA
Colleen P. Davis, Christian D. Frazar, Meng-Fan Huang, Caitlin Jacques, J. Thomas Kolar, Joshua D. Smith, Chia-Lin Wei, Jeffrey M. Weiss, Christina Zakarian, Sean R. McGee, Patrick M. Nielsen, Erica Ryke & Tristan Shaffer
Pathology and Biorepository Core, Van Andel Institute, Grand Rapids, MI, USA
Daniel C. Rohrer, Christina Missler & Brianne E. Livermore
Department of Neuroscience, City University of Hong Kong, Hong Kong, China
Xiaowei Zhu
Department of Physics, Harvard University, Boston, MA, USA
Rohan Thakur & David A. Weitz
Department of Urology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA
Jonathan Evan Shoag
Case Comprehensive Cancer Center, Cleveland, OH, USA
Jonathan Evan Shoag
Institute for Systems Genetics, NYU Grossman School of Medicine, New York, NY, USA
Jimin Tan
Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA
Aristotelis Tsirigos
Department of Pathology, NYU Grossman School of Medicine, New York, NY, USA
Aristotelis Tsirigos
Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA
Xiaofeng Zhu
T.H.H.C., J.W.O., E.A.L. and F.M.V. wrote the manuscript, with input, review and feedback from all other authors. J.W.O., T.H.H.C., Y.A.C., N.S.L. and A.V. made the figures. A.C.L. was substantially involved in UM1 DA058219, UM1 DA058220, UM1 DA058229, UM1 DA058230, UM1 DA058235 and UM1 DA058236, consistent with the role as Program Officer; and is also the NIH Working Group Coordinator, and has involvement with the remaining awards, consistent with this role.